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Molecular mechanisms of sexually dimorphic nervous system patterning in flies and worms

Abstract:

Male and female brains display anatomical and functional differences. Such differences are observed in species across the animal kingdom, including humans, but have been particularly well-studied in two classic animal model systems, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans. Here we summarize recent advances in understanding how the worm and fly brain acquire sexually dimorphic features during development. We highlight the advantages of each system, illustr...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
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Name:
Wellcome Trust
Grant:
106189/Z/14/Z
Publisher:
Annual Reviews
Journal:
Annual Review of Cell and Developmental Biology More from this journal
Volume:
57
Pages:
519-547
Publication date:
2021-10-06
Acceptance date:
2021-07-02
DOI:
ISSN:
1081-0706
Language:
English
Keywords:
Pubs id:
1197228
Local pid:
pubs:1197228
Deposit date:
2021-10-01

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