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Journal article

Effects of prolonged fasting and sustained lipolysis on insulin secretion and insulin sensitivity in normal subjects.

Abstract:

Normal beta-cells adjust their function to compensate for any decrease in insulin sensitivity. Our aim was to explore whether a prolonged fast would allow a study of the effects of changes in circulating free fatty acid (FFA) levels on insulin secretion and insulin sensitivity and whether any potential effects could be reversed by the antilipolytic agent acipimox. Fourteen (8 female, 6 male) healthy young adults (aged 22.8-26.9 yr) without a family history of diabetes and a body mass index of...

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Publication status:
Published

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Publisher copy:
10.1152/ajpendo.90613.2008

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
Journal:
American journal of physiology. Endocrinology and metabolism More from this journal
Volume:
296
Issue:
3
Pages:
E454-E461
Publication date:
2009-03-01
DOI:
EISSN:
1522-1555
ISSN:
0193-1849
Language:
English
Keywords:
Pubs id:
pubs:328908
UUID:
uuid:d0696264-2c9a-49e1-83b6-d594ea24ad97
Local pid:
pubs:328908
Source identifiers:
328908
Deposit date:
2012-12-19

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