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Journal article

Distinct mechanisms underlie pattern formation in the skin and skin appendages.

Abstract:

Patterns form with the break of homogeneity and lead to the emergence of new structure or arrangement. There are different physiological and pathological mechanisms that lead to the formation of patterns. Here, we first introduce the basics of pattern formation and their possible biological basis. We then discuss different categories of skin patterns and their potential underlying molecular mechanisms. Some patterns, such as the lines of Blaschko and Naevus, are based on cell lineage and gene...

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Publisher copy:
10.1002/bdrc.20075

Authors


Widelitz, RB More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
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Journal:
Birth defects research. Part C, Embryo today : reviews
Volume:
78
Issue:
3
Pages:
280-291
Publication date:
2006-09-05
DOI:
EISSN:
1542-9768
ISSN:
1542-975X
URN:
uuid:d0517229-8d57-4020-87a8-8a5a28bde800
Source identifiers:
20769
Local pid:
pubs:20769

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