Distinct mechanisms underlie pattern formation in the skin and skin appendages.
Patterns form with the break of homogeneity and lead to the emergence of new structure or arrangement. There are different physiological and pathological mechanisms that lead to the formation of patterns. Here, we first introduce the basics of pattern formation and their possible biological basis. We then discuss different categories of skin patterns and their potential underlying molecular mechanisms. Some patterns, such as the lines of Blaschko and Naevus, are based on cell lineage and gene...Expand abstract
- Publisher copy:
- Birth defects research. Part C, Embryo today : reviews
- Publication date:
- Source identifiers:
- Local pid:
- Copyright date: