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MHC class I and class II structures.

Abstract:
The basic structures of MHC class I and class II molecules are now well established. Over the past twelve months structural data on MHC class I molecules have provided details of the peptide binding groove for a number of alleles and have elaborated the mechanisms that allow binding of a range of peptides. Recent MHC class II structures have illustrated the mode of peptide binding both in mature complexes and in the MHC class II complex with a fragment of invariant chain (CLIP) during maturation.
Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
Journal:
Current opinion in immunology More from this journal
Volume:
9
Issue:
1
Pages:
75-79
Publication date:
1997-02-01
DOI:
EISSN:
1879-0372
ISSN:
0952-7915
Language:
English
Keywords:
Pubs id:
pubs:25372
UUID:
uuid:d04d7c85-f476-49b5-a25d-bb8dd197429f
Local pid:
pubs:25372
Source identifiers:
25372
Deposit date:
2012-12-19

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