Conference item icon

Conference item

Cancer predisposition syndromes: Lessons for truly precision medicine

Abstract:

Cancer predisposition syndromes are typically uncommon, monogenic, high-penetrance disorders. Despite their rarity, they have proven to be highly clinically relevant in directing cancer prevention strategies. As such, they are similar to an expanding class of low-frequency somatic mutations that are associated with a striking prognostic or predictive effect in the tumours in which they occur. This talk aims to highlight these commonalities, with particular reference to mutations in the proofr...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/path.4984

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Oxford college:
Wolfson College
Role:
Author
Publisher:
Wiley
Host title:
10th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain and Ireland
Journal:
10th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland More from this journal
Publication date:
2017-09-25
Acceptance date:
2017-06-15
DOI:
ISSN:
0022-3417
Pubs id:
pubs:735202
UUID:
uuid:d0469cbf-e07b-40fd-b336-a56325e8ac25
Local pid:
pubs:735202
Source identifiers:
735202
Deposit date:
2017-10-13

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP