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Immunoglobulin superfamily cell adhesion molecules: zippers and signals.

Abstract:

The latest structural studies of immunoglobulin superfamily cell adhesion molecules are driving a shift in perspective; increasingly the view is not focused solely on the individual molecule but rather is on the molecular assembly. Two common themes are emerging, revealing mechanisms for ectodomain-dependent regulation of cell surface receptors' signalling abilities. The first is the propensity of many such molecules to arrange in zipper-type or array-type assemblies driven by a network of hi...

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Publication status:
Published

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Publisher copy:
10.1016/j.ceb.2007.09.010

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Structural Biology
Journal:
Current opinion in cell biology
Volume:
19
Issue:
5
Pages:
543-550
Publication date:
2007-10-05
DOI:
EISSN:
1879-0410
ISSN:
0955-0674
URN:
uuid:d0298fe9-ab3d-4915-989c-b44c9c7caa00
Source identifiers:
13521
Local pid:
pubs:13521

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