Journal article icon

Journal article

Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese.

Abstract:

The genetic basis for susceptibility to malaria has been studied widely in African populations but less is known of the contribution of specific genetic variants in Asian populations. We genotyped 67 single-nucleotide polymorphisms (SNPs) in 1030 severe malaria cases and 2840 controls from Vietnam. After data quality control, genotyping data of 956 cases and 2350 controls were analysed for 65 SNPs (3 gender confirmation, 62 positioned in/near 42 malarial candidate genes). A total of 14 SNPs w...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/gene.2012.25

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Rockett, KA More by this author
Expand authors...
Journal:
Genes and immunity
Volume:
13
Issue:
6
Pages:
503-508
Publication date:
2012-09-05
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
URN:
uuid:d01f44ab-f09f-4053-b68b-ed2ed8135a0f
Source identifiers:
334694
Local pid:
pubs:334694

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP