Journal article icon

Journal article

Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe.

Abstract:

Polyadenylation of pre-mRNAs, a critical step in eukaryotic gene expression, is mediated by cis elements collectively called the polyadenylation signal. Genome-wide analysis of such polyadenylation signals was missing in fission yeast, even though it is an important model organism. We demonstrate that the canonical AATAAA motif is the most frequent and functional polyadenylation signal in Schizosaccharomyces pombe. Using analysis of RNA-Seq data sets from cells grown under various physiologic...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1261/rna.040675.113

Authors


Schlackow, M More by this author
Marguerat, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Bähler, J More by this author
Expand authors...
Journal:
RNA (New York, N.Y.)
Volume:
19
Issue:
12
Pages:
1617-1631
Publication date:
2013-12-05
DOI:
EISSN:
1469-9001
ISSN:
1355-8382
URN:
uuid:d0135cc7-b168-49ef-9a62-17864ccf2309
Source identifiers:
435862
Local pid:
pubs:435862

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP