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Journal article

Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe.

Abstract:

Polyadenylation of pre-mRNAs, a critical step in eukaryotic gene expression, is mediated by cis elements collectively called the polyadenylation signal. Genome-wide analysis of such polyadenylation signals was missing in fission yeast, even though it is an important model organism. We demonstrate that the canonical AATAAA motif is the most frequent and functional polyadenylation signal in Schizosaccharomyces pombe. Using analysis of RNA-Seq data sets from cells grown under various physiologic...

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Publication status:
Published

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Publisher copy:
10.1261/rna.040675.113

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
RNA (New York, N.Y.) More from this journal
Volume:
19
Issue:
12
Pages:
1617-1631
Publication date:
2013-12-01
DOI:
EISSN:
1469-9001
ISSN:
1355-8382

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