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Treating to target in psoriatic arthritis: assessing real-world outcomes and optimising therapeutic strategy for adults with psoriatic arthritis-study protocol for the MONITOR-PsA study, a trials within cohorts study design

Abstract:
Background The Tight Control of psoriatic arthritis (TICOPA) trial confirmed improved clinical outcomes with a treat to target (T2T) strategy in psoriatic arthritis (PsA). This consisted of 4-weekly review and escalation of ‘step up’ therapy (single disease modifying therapy (DMARD), combination DMARDs and then biologics) based on remission criteria. Based on this, a T2T approach is supported by European PsA treatment recommendations. However, it is not commonly implemented i... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13063-021-05142-7

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0003-3464-3867
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National Institute for Health Research More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Volume:
22
Issue:
1
Article number:
185
Publication date:
2021-03-04
Acceptance date:
2021-02-20
DOI:
EISSN:
1745-6215
Pmid:
33663566
Language:
English
Keywords:
Pubs id:
1166223
Local pid:
pubs:1166223
Deposit date:
2021-06-02

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