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Journal article

Effect of HLA class II genotype on T helper lymphocyte responses and viral control in hepatitis C virus infection.

Abstract:

Hepatitis C virus (HCV) infection is very common worldwide, but has a broad range of outcomes. A minority of patients are able to clear infection spontaneously, and this is thought to be due to the emergence and maintenance of effective cell-mediated immunity, particularly CD4+ T lymphocyte responses. Furthermore, genetic studies have indicated that HLA class II genotype strongly influences the outcome of infection. We have therefore investigated the influence of the protective HLA class II h...

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Publication status:
Published

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Journal:
Journal of viral hepatitis
Volume:
8
Issue:
3
Pages:
174-179
Publication date:
2001-05-01
DOI:
EISSN:
1365-2893
ISSN:
1352-0504
Source identifiers:
13955

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