- Abstract:
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Induced regulatory T cells (iTreg) play an important role in the induction of tolerance to self and non-self antigens. Harnessing their suppressive potential has therapeutic implications for the treatment of autoimmune conditions and transplant rejection. Although the role of TGFβ-conditioned iTreg in natural and therapeutic tolerance is indisputable, their mechanism of action as well as factors that influence their function and stability in vivo remain unclear. Here it is shown t...
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- Division:
- MSD
- Department:
- Pathology Dunn School
- Role:
- Supervisor
- Division:
- MSD
- Department:
- Pathology Dunn School
- Role:
- Supervisor
- Publication date:
- 2010
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
-
uuid:cffc275b-d32c-495e-a1da-55421a57e7e7
- Local pid:
- ora:12095
- Language:
- English
- Subjects:
- Copyright holder:
- Chen, Y
- Copyright date:
- 2010
Thesis
Induced regulatory T cells in transplantation tolerance
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Authors
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+ Waldmann, H
+ Howie, D
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