Journal article icon

Journal article

Helix kinks are equally prevalent in soluble and membrane proteins

Abstract:

Helix kinks are a common feature of α-helical membrane proteins, but are thought to be rare in soluble proteins. In this study we find that kinks are a feature of long α-helices in both soluble and membrane proteins, rather than just transmembrane α-helices. The apparent rarity of kinks in soluble proteins is due to the relative infrequency of long helices (≥20 residues) in these proteins. We compare length-matched sets of soluble and membrane helices, and find that the frequency of kinks, th...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/prot.24550

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
Journal:
Proteins: Structure, Function and Bioinformatics
Volume:
82
Issue:
9
Pages:
1960-1970
Publication date:
2014-01-01
DOI:
EISSN:
1097-0134
ISSN:
0887-3585
Source identifiers:
483282
Pubs id:
pubs:483282
UUID:
uuid:cfeedfef-2669-45ca-9930-e5bf35699303
Local pid:
pubs:483282
Deposit date:
2014-10-15

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP