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The structure and function of integrins

Abstract:

Integrins are a family of αβ heterodimeric cell surface glycoproteins formed by the noncovalent association of a specific integrin α and β subunit. At present 16 different integrin α subunits and 8 different integrin β subunits have been identified, which can associate in various combinations to produce over 20 different integrin αβ heterodimeric receptors. The leukocyte integrins LFA-1 (αLβ2, CD11a/CD18), Mac-1 (αMβ2, CD11b/CD18) and p150,95 (αXβ2, CD11c/CD18) are formed by the non-coval...

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Institution:
University of Oxford
Department:
Dept. of Biochemistry
Role:
Author
Publication date:
1997
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
UUID:
uuid:cfdfd40c-b350-4500-83e4-2650f9fe455d
Local pid:
td:602819883
Source identifiers:
602819883
Deposit date:
2014-07-22

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