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Time course of hypoxic pulmonary vasoconstriction: a rabbit model of regional hypoxia.

Abstract:

There is disagreement in the literature about the time required for hypoxic constriction of pulmonary vessels to reach its full intensity. Some studies suggest that only minutes are required, others that several hours are needed. We examined the time course over 6 h of changes in pulmonary shunt (as a fraction of cardiac output) following induction of unilateral hypoxia by collapse or liquid filling of the left lung in 47 anesthetized rabbits. The time course was examined at four degrees of l...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
American journal of respiratory and critical care medicine More from this journal
Volume:
155
Issue:
1
Pages:
216-221
Publication date:
1997-01-01
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
Language:
English
Keywords:
Pubs id:
pubs:113328
UUID:
uuid:cfccd338-8114-459b-93a1-0edc4014a7be
Local pid:
pubs:113328
Source identifiers:
113328
Deposit date:
2013-11-17

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