Journal article
Antigenicity and Immunogenicity in HIV-1 Antibody-Based Vaccine Design.
- Abstract:
-
Neutralizing antibodies can protect from infection by immunodeficiency viruses. However, the induction by active vaccination of antibodies that can potently neutralize a broad range of circulating virus strains is a goal not yet achieved, despite more than 2 decades of research. Here we review progress made in the field, from early empirical studies to today's rational structure-based vaccine antigen design. We discuss the existence of broadly neutralizing antibodies, their implications for e...
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Bibliographic Details
- Journal:
- Journal of AIDS and clinical research
- Volume:
- S8
- Pages:
- 3
- Publication date:
- 2012-01-01
- DOI:
- EISSN:
-
2155-6113
- ISSN:
-
2155-6113
- Source identifiers:
-
367639
Item Description
- Language:
- English
- Pubs id:
-
pubs:367639
- UUID:
-
uuid:cfbe4b09-217b-4a05-89ac-68414f3e0320
- Local pid:
- pubs:367639
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2012
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