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Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2.

Abstract:

Both human and murine cytotoxic T cells (CTL) elicited in response to infection with influenza A viruses have been shown to be specific for internal viral proteins, such as the matrix and nucleoprotein. Individual CTL epitopes have been identified in the nucleoprotein by successfully substituting short synthetic peptides for the intact virus in the preparation of target cells in cytotoxicity assays. The defined peptide epitopes have each been recognized by CTL in association with individual c...

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Publication status:
Published

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Publisher copy:
10.1038/326881a0

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Strategic
Role:
Author
Journal:
Nature
Volume:
326
Issue:
6116
Pages:
881-882
Publication date:
1987-04-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Source identifiers:
72169
Language:
English
Keywords:
Pubs id:
pubs:72169
UUID:
uuid:cfba8510-e459-4c6f-a9df-d52046da64d5
Local pid:
pubs:72169
Deposit date:
2012-12-19

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