Elevated arterial pulse pressure and blood pressure (BP) can lead to atrophy of cerebral white matter (WM), potentially attributable to shared genetic factors. We calculated the magnitude of shared genetic variance between BP and fractional anisotropy of water diffusion, a sensitive measurement of WM integrity in a well-characterized population of Mexican Americans. The patterns of whole-brain and regional genetic overlap between BP and fractional anisotropy were interpreted in the context th...Expand abstract
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- Peer review status:
- Peer reviewed
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- Copyright holder:
- American Heart Association, Inc.
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- Copyright © 2010 American Heart Association, Inc. All rights reserved. The full text of this article is not currently available in ORA.
Blood pressure and cerebral white matter share common genetic factors in Mexican Americans
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