- Abstract:
-
Elevated arterial pulse pressure and blood pressure (BP) can lead to atrophy of cerebral white matter (WM), potentially attributable to shared genetic factors. We calculated the magnitude of shared genetic variance between BP and fractional anisotropy of water diffusion, a sensitive measurement of WM integrity in a well-characterized population of Mexican Americans. The patterns of whole-brain and regional genetic overlap between BP and fractional anisotropy were interpreted in the context th...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1161/HYPERTENSIONAHA.110.162206
-
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- Publisher:
- American Heart Association Publisher's website
- Journal:
- Hypertension Journal website
- Volume:
- 57
- Issue:
- 2
- Pages:
- 330-335
- Publication date:
- 2011-02-01
- DOI:
- EISSN:
-
1524-4563
- ISSN:
-
0194-911X
- URN:
-
uuid:cfa342b3-7cb8-492b-8bc2-13835388c733
- Source identifiers:
-
445994
- Local pid:
- pubs:445994
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- American Heart Association, Inc.
- Copyright date:
- 2011
- Notes:
- Copyright © 2010 American Heart Association, Inc. All rights reserved. The full text of this article is not currently available in ORA.
Journal article
Blood pressure and cerebral white matter share common genetic factors in Mexican Americans
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