Journal article
A randomised trial of malaria vaccine R21/Matrix-M™ with and without antimalarial drugs in Thai adults
- Abstract:
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In preparation for mass vaccinations with R21/Matrix-M™ combined with mass administrations of dihydroartemisinin, piperaquine, and a single low dose primaquine we assessed the tolerability, safety, and potential interactions of this combination affecting immunogenicity or pharmacokinetics. 120 healthy Thai volunteers were randomised to receive either antimalarials combined with vaccinations (n = 50), vaccinations alone (n = 50), or antimalarials only (n = 20). Three rounds of vaccines and ant...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1038/s41541-024-00920-1
Authors
Bibliographic Details
- Publisher:
- Nature Research
- Journal:
- npj Vaccines More from this journal
- Volume:
- 9
- Issue:
- 1
- Article number:
- 124
- Publication date:
- 2024-07-06
- Acceptance date:
- 2024-06-27
- DOI:
- EISSN:
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2059-0105
- ISSN:
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2059-0105
Item Description
- Language:
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English
- Pubs id:
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2013033
- Local pid:
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pubs:2013033
- Source identifiers:
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2093837
- Deposit date:
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2024-07-07
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