Prediction of benefit from carotid endarterectomy in individual patients: a risk-modelling study. European Carotid Surgery Trialists' Collaborative Group.

Journal article

BACKGROUND: Carotid endarterectomy lowers the risk of carotid territory ipsilateral ischaemic stroke, and is the treatment of choice, in patients with recently symptomatic 70-99% carotid stenosis. However, the 3-year risk of stroke on medical treatment alone is only about 20%. We investigated whether the efficacy of endarterectomy would be improved if patients with a high risk of stroke on medical treatment and a low risk of operative stroke or death could be identified. METHODS: We developed...

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Authors: Rothwell, P; Warlow, C

• Publication status: Published
• Journal: Lancet
• Volume: 353
• Issue: 9170
• Pages: 2105-2110
• Publication date: 1999-06-01
• DOI: 10.1016/s0140-6736(98)11415-0
• EISSN: 1474-547X
• ISSN: 0140-6736
• Language: English
• Keywords: Decision Support Techniques; Models, Cardiovascular; Reproducibility of Results; Patient Selection; Actuarial Analysis; Prognosis; Proportional Hazards Models; Endarterectomy, Carotid; Cerebrovascular Disorders; Brain Ischemia; Risk; Carotid Stenosis; Humans