A gene expression profiling approach assessing celecoxib in a randomized controlled trial in prostate cancer.

Sooriakumaran, P; Macanas-Pirard, P; Bucca, G; Henderson, A; Langley, SE; Laing, RW; Smith, CP; Laing, EE; Coley, HM

Abstract:

BACKGROUND: We performed a pilot study, looking at the COX-2 inhibitor celecoxib, on newly diagnosed prostate cancer patients in the neo-adjuvant setting using DNA microarray analysis. PATIENTS AND METHODS: This was a single-blinded, randomized controlled phase II presurgical (radical prostatectomy) 28-day trial of celecoxib versus no drug in patients with localized T1-2 N0 M0 prostate cancer. cDNA microarray analysis was carried out on prostate cancer biopsies taken from freshly obtained ra...

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APA Style

Sooriakumaran, P., Macanas-Pirard, P., Bucca, G., Henderson, A., Langley, S. E., Laing, R. W., Smith, C. P., Laing, E. E., & Coley, H. M. (2009). A gene expression profiling approach assessing celecoxib in a randomized controlled trial in prostate cancer. Cancer Genomics and Proteomics, 6(2), 93–99.

MLA Style

Sooriakumaran, P., et al. “A Gene Expression Profiling Approach Assessing Celecoxib in a Randomized Controlled Trial in Prostate Cancer.” Cancer Genomics and Proteomics, vol. 6, no. 2, Cancer genomics and proteomics, 2009, pp. 93–99.

Chicago Style

Sooriakumaran, P, P Macanas-Pirard, G Bucca, A Henderson, SE Langley, RW Laing, CP Smith, EE Laing, and HM Coley. 2009. “A Gene Expression Profiling Approach Assessing Celecoxib in a Randomized Controlled Trial in Prostate Cancer.” Cancer Genomics and Proteomics 6 (2): 93–99.
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Authors

+ Sooriakumaran, P More by this author

Institution:

University of Oxford

Department:

Oxford, MSD, Surgical Sciences

Macanas-Pirard, P More by this author

Bucca, G More by this author

Henderson, A More by this author

Langley, SE More by this author

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Bibliographic Details

Journal:: Cancer genomics and proteomics
Volume:: 6
Issue:: 2
Pages:: 93-99
Publication date:: 2009
EISSN:: 1790-6245
ISSN:: 1109-6535
URN:: uuid:cf37ed9a-da47-4811-819c-f9be1a3e660a
Source identifiers:: 414579
Local pid:: pubs:414579

Item Description

Language:: English
Keywords:: Gene Expression Profiling

DNA, Complementary

DNA Primers

Prostatic Neoplasms

Humans

Base Sequence

Cyclooxygenase Inhibitors

Pyrazoles

Oligonucleotide Array Sequence Analysis

Single-Blind Method

Polymerase Chain Reaction

Male

Sulfonamides

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