Journal article
Increased frequencies of CD4+ CD25(high) regulatory T cells in acute dengue infection.
- Abstract:
-
Dengue virus infection is an increasingly important tropical disease, causing 100 million cases each year. Symptoms range from mild febrile illness to severe hemorrhagic fever. The pathogenesis is incompletely understood, but immunopathology is thought to play a part, with antibody-dependent enhancement and massive immune activation of T cells and monocytes/macrophages leading to a disproportionate production of proinflammatory cytokines. We sought to investigate whether a defective populatio...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Journal of experimental medicine
- Volume:
- 204
- Issue:
- 5
- Pages:
- 979-985
- Publication date:
- 2007-05-01
- DOI:
- EISSN:
-
1540-9538
- ISSN:
-
0022-1007
- Source identifiers:
-
33826
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:33826
- UUID:
-
uuid:cf31bb14-7fcb-4beb-a6ad-f55fb564bf8b
- Local pid:
- pubs:33826
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2007
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