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Journal article

Increased frequencies of CD4+ CD25(high) regulatory T cells in acute dengue infection.

Abstract:

Dengue virus infection is an increasingly important tropical disease, causing 100 million cases each year. Symptoms range from mild febrile illness to severe hemorrhagic fever. The pathogenesis is incompletely understood, but immunopathology is thought to play a part, with antibody-dependent enhancement and massive immune activation of T cells and monocytes/macrophages leading to a disproportionate production of proinflammatory cytokines. We sought to investigate whether a defective populatio...

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Publication status:
Published

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Publisher copy:
10.1084/jem.20061381

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Journal:
Journal of experimental medicine
Volume:
204
Issue:
5
Pages:
979-985
Publication date:
2007-05-01
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
Source identifiers:
33826
Language:
English
Keywords:
Pubs id:
pubs:33826
UUID:
uuid:cf31bb14-7fcb-4beb-a6ad-f55fb564bf8b
Local pid:
pubs:33826
Deposit date:
2012-12-19

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