- Abstract:
-
Dengue virus infection is an increasingly important tropical disease, causing 100 million cases each year. Symptoms range from mild febrile illness to severe hemorrhagic fever. The pathogenesis is incompletely understood, but immunopathology is thought to play a part, with antibody-dependent enhancement and massive immune activation of T cells and monocytes/macrophages leading to a disproportionate production of proinflammatory cytokines. We sought to investigate whether a defective populatio...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1084/jem.20061381
-
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- Journal:
- The Journal of experimental medicine
- Volume:
- 204
- Issue:
- 5
- Pages:
- 979-985
- Publication date:
- 2007-05-05
- DOI:
- EISSN:
-
1540-9538
- ISSN:
-
0022-1007
- URN:
-
uuid:cf31bb14-7fcb-4beb-a6ad-f55fb564bf8b
- Source identifiers:
-
33826
- Local pid:
- pubs:33826
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
Increased frequencies of CD4+ CD25(high) regulatory T cells in acute dengue infection.
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