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Journal article

Increased frequencies of CD4+ CD25(high) regulatory T cells in acute dengue infection.

Abstract:

Dengue virus infection is an increasingly important tropical disease, causing 100 million cases each year. Symptoms range from mild febrile illness to severe hemorrhagic fever. The pathogenesis is incompletely understood, but immunopathology is thought to play a part, with antibody-dependent enhancement and massive immune activation of T cells and monocytes/macrophages leading to a disproportionate production of proinflammatory cytokines. We sought to investigate whether a defective populatio...

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Publication status:
Published

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Publisher copy:
10.1084/jem.20061381

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
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Journal:
The Journal of experimental medicine
Volume:
204
Issue:
5
Pages:
979-985
Publication date:
2007-05-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:cf31bb14-7fcb-4beb-a6ad-f55fb564bf8b
Source identifiers:
33826
Local pid:
pubs:33826

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