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Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification.

Abstract:
High throughput screening combined with efficient datamining and parallel synthesis led to the discovery of a novel series of indolines showing potent in vitro ghrelin receptor agonist activity and acceleration of gastric emptying in rats.
Publication status:
Published

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Publisher copy:
10.1016/j.bmcl.2007.09.067

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Genomics Consortium
Role:
Author
Journal:
Bioorganic and medicinal chemistry letters More from this journal
Volume:
17
Issue:
23
Pages:
6584-6587
Publication date:
2007-12-01
DOI:
EISSN:
1464-3405
ISSN:
0960-894X
Language:
English
Keywords:
Pubs id:
pubs:34011
UUID:
uuid:cf301f77-8152-4a9c-a332-627b1b89e611
Local pid:
pubs:34011
Source identifiers:
34011
Deposit date:
2012-12-19

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