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The magnocellular mediodorsal thalamus is necessary for memory acquisition, but not retrieval.

Abstract:

Damage to the magnocellular mediodorsal thalamic nucleus (MDmc) in the human brain is associated with both retrograde and anterograde amnesia. In the present study we made selective neurotoxic MDmc lesions in rhesus monkeys and compared the effects of these lesions on memory acquisition and retrieval. Monkeys learned 300 unique scene discriminations preoperatively and retention was assessed in a one-trial preoperative retrieval test. Bilateral neurotoxic lesions of the MDmc, produced by 10 x ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
28
Issue:
1
Pages:
258-263
Publication date:
2008-01-05
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:cf255f9c-0a95-413c-9b97-15c1a2d0c9ce
Source identifiers:
9806
Local pid:
pubs:9806

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