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Journal article

Interaction between the C. elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly

Abstract:

Centrioles are microtubule-based organelles that organise the microtubule network and seed the formation of cilia and flagella. New centrioles assemble through a step-wise process dependent notably on the centriolar protein SAS-5 in Caenorhabditis elegans. SAS-5 and its functional homologues in other species form oligomers that bind the centriolar proteins SAS-6 and SAS-4, thereby forming an evolutionarily conserved structural core at the onset of organelle assembly. Here, we repor...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Version of record

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Publisher copy:
10.1091/mbc.E17-06-0412

Authors


Bianchi, S More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Hilbert, M More by this author
Leidel, SA More by this author
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Engineering and Physical Sciences Research Council More from this funder
Publisher:
American Society for Cell Biology Publisher's website
Journal:
Molecular Biology of the Cell Journal website
Volume:
29
Issue:
6
Pages:
683-771
Publication date:
2018-01-24
Acceptance date:
2018-01-17
DOI:
EISSN:
1939-4586
ISSN:
1059-1524
Pubs id:
pubs:820398
URN:
uri:cf1ca599-032e-4b65-8327-36de9507dc7d
UUID:
uuid:cf1ca599-032e-4b65-8327-36de9507dc7d
Local pid:
pubs:820398

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