Journal article icon

Journal article

The Brain Ages Optimally to Model Its Environment: Evidence from Sensory Learning over the Adult Lifespan

Abstract:

The aging brain shows a progressive loss of neuropil, which is accompanied by subtle changes in neuronal plasticity, sensory learning and memory. Neurophysiologically, aging attenuates evoked responses-including the mismatch negativity (MMN). This is accompanied by a shift in cortical responsivity from sensory (posterior) regions to executive (anterior) regions, which has been interpreted as a compensatory response for cognitive decline. Theoretical neurobiology offers a simpler explanation f...

Expand abstract

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
PLoS Computational Biology
Volume:
10
Issue:
1
Publication date:
2014-01-01
DOI:
EISSN:
1553-7358
ISSN:
1553-734X
Language:
English
Pubs id:
pubs:460439
UUID:
uuid:cf05320f-728f-424c-a2c8-5165534c6d78
Local pid:
pubs:460439
Source identifiers:
460439
Deposit date:
2014-06-17

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP