Journal article
Sclerostin expression in bone tumours and tumour-like lesions
- Abstract:
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Aims
To assess the immunophenotypic and mRNA expression of sclerostin in human skeletal tissues and in a wide range of benign and malignant bone tumours and tumour-like lesions.
Methods and Results:
Sclerostin expression was evaluated by immunohistochemistry and quantitative PCR. In lamellar and woven bone, there was strong sclerostin expression by osteocytes. Osteoblasts and other cell types in bone were negative. Hypertrophic chondrocytes in the gr...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
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(Accepted manuscript, pdf, 978.5KB)
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- Publisher copy:
- 10.1111/his.12953
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Authors
Funding
National Institute of Health Research
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The Sasakawa Foundation
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The Rosetrees Trust
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Sarcoma
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The Bone Cancer Research Trust
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Histopathology Journal website
- Volume:
- 69
- Issue:
- 3
- Pages:
- 470-478
- Publication date:
- 2016-02-20
- Acceptance date:
- 2016-02-15
- DOI:
- EISSN:
-
1365-2559
- ISSN:
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0309-0167
- Source identifiers:
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605675
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:605675
- UUID:
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uuid:cf047b5f-eaf9-4eac-b5e2-dd22324146eb
- Local pid:
- pubs:605675
- Deposit date:
- 2016-02-26
Terms of use
- Copyright holder:
- Wiley
- Copyright date:
- 2016
- Notes:
- © 2016 John Wiley and Sons Ltd. This is the accepted manuscript version of the article. The final version is available from Wiley at: https://doi.org/10.1111/his.12953
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