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Journal article

Sclerostin expression in bone tumours and tumour-like lesions

Abstract:

Aims

To assess the immunophenotypic and mRNA expression of sclerostin in human skeletal tissues and in a wide range of benign and malignant bone tumours and tumour-like lesions.

Methods and Results:

Sclerostin expression was evaluated by immunohistochemistry and quantitative PCR. In lamellar and woven bone, there was strong sclerostin expression by osteocytes. Osteoblasts and other cell types in bone were negative. Hypertrophic chondrocytes in the gr...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1111/his.12953

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
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National Institute of Health Research More from this funder
The Sasakawa Foundation More from this funder
The Rosetrees Trust More from this funder
The Bone Cancer Research Trust More from this funder
Publisher:
Wiley Publisher's website
Journal:
Histopathology Journal website
Volume:
69
Issue:
3
Pages:
470-478
Publication date:
2016-02-20
Acceptance date:
2016-02-15
DOI:
EISSN:
1365-2559
ISSN:
0309-0167
Source identifiers:
605675
Language:
English
Keywords:
Pubs id:
pubs:605675
UUID:
uuid:cf047b5f-eaf9-4eac-b5e2-dd22324146eb
Local pid:
pubs:605675
Deposit date:
2016-02-26

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