Journal article icon

Journal article

Development of sensitive immunoassays for free and total human glandular kallikrein 2.

Abstract:

BACKGROUND: Free and total human kallikrein 2 (hK2) might improve the discrimination between prostate cancer and benign prostatic hyperplasia. Concentrations of hK2 are 100-fold lower than concentrations of prostate-specific antigen (PSA); therefore, an hK2 assay must have a low detection limit and good specificity. METHODS: PSA- and hK2-specific monoclonal antibodies were used in solid-phase, two-site immunofluorometric assays to detect free and total hK2. The total hK2 assay used PSA-speci...

Expand abstract

Actions


Access Document


Authors


Väisänen, V More by this author
Eriksson, S More by this author
Ivaska, KK More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Expand authors...
Journal:
Clinical chemistry
Volume:
50
Issue:
9
Pages:
1607-1617
Publication date:
2004-09-05
DOI:
EISSN:
1530-8561
ISSN:
0009-9147
URN:
uuid:cf038b56-837f-4104-b47a-9e135378589a
Source identifiers:
365989
Local pid:
pubs:365989

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP