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Lithium overdose and delayed severe neurotoxicity: timing for renal replacement therapy and restarting of lithium

Abstract:

This is a case report of a man in his 60s who presented to an English hospital following a significant lithium overdose. He was monitored for 24 hours, and then renal replacement therapy was initiated after assessment by the renal team. As soon as the lithium level returned to normal therapeutic levels (from 4.7 mEq/L to 0.67 mEq/L), lithium was restarted by the medical team. At this point, the patient developed new slurred speech and later catatonia. In this case report, we discuss the facto...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1136/bcr-2017-222453

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
ORCID:
0000-0001-7848-1295
More by this author
ORCID:
0000-0003-0657-4606
Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Case Reports Journal website
Volume:
2017
Pages:
bcr-2017-222453
Publication date:
2018-10-25
Acceptance date:
2018-10-10
DOI:
ISSN:
1757-790X
Pubs id:
pubs:924073
URN:
uri:cf021025-a0de-4d9e-b00a-368d5192353b
UUID:
uuid:cf021025-a0de-4d9e-b00a-368d5192353b
Local pid:
pubs:924073
Language:
English

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