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Novel approaches to improve the therapeutic index of head and neck radiotherapy: an analysis of data from the PARSPORT randomised phase III trial.

Abstract:

PURPOSE: Subjective xerostomia is a common side-effect following radiotherapy for the treatment of head-and-neck cancer. Standard mean dose models previously used to model xerostomia only that partially predict the occurrence of xerostomia. Studies in animal models have suggested that there are regional variations in the radiosensitivity of the parotid glands. In this work we tested the hypothesis that this is also true for the human parotid gland. METHODS: We present novel dose-response mode...

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Journal:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology More from this journal
Volume:
103
Issue:
1
Pages:
82-87
Publication date:
2012-04-01
DOI:
EISSN:
1879-0887
ISSN:
0167-8140
Language:
English
Keywords:
Pubs id:
pubs:320404
UUID:
uuid:cf00d8a1-928c-4a65-9863-355f83ac266e
Local pid:
pubs:320404
Source identifiers:
320404
Deposit date:
2013-11-16

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