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A randomised controlled trial of artemether-lumefantrine versus artesunate for uncomplicated plasmodium falciparum treatment in pregnancy.

Abstract:

BACKGROUND: To date no comparative trials have been done, to our knowledge, of fixed-dose artemisinin combination therapies (ACTs) for the treatment of Plasmodium falciparum malaria in pregnancy. Evidence on the safety and efficacy of ACTs in pregnancy is needed as these drugs are being used increasingly throughout the malaria-affected world. The objective of this study was to compare the efficacy, tolerability, and safety of artemether-lumefantrine, the most widely used fixed ACT, with 7 d ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.0050253

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Institution:
University of Oxford
Role:
Author
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Name:
World Bank
Grant:
A41150
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Name:
World Health Organization
Grant:
A41150
More from this funder
Name:
United Nations Development Programme
Grant:
A41150
Publisher:
Public Library of Science
Journal:
PLoS Med More from this journal
Volume:
5
Issue:
12
Article number:
e253
Publication date:
2008-12-01
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Language:
English
Keywords:
UUID:
uuid:ceeb35fa-b79a-4ce0-8fb2-ecf1ece1c2f3
Local pid:
pubs:12412
Source identifiers:
12412
Deposit date:
2012-12-19

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