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Abandoning presumptive antimalarial treatment for febrile children aged less than five years - a case of running before we can walk?

Abstract:

Background to the Debate Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.1000015

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Institution:
"KEMRI-Wellcome Trust Programme, Centre for Geographic Medicine Resarch-Coast, Nairobi, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Paediatrics,Department of
Role:
Author
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Institution:
"Joint Malaria Programme, Kilimanjaro Christian Medical College, Moshi, United Republic of Tanzania", "London School of Hygiene & Tropical Medicine, London, UK"
Department:
Health Policy Unit
Role:
Author
More by this author
Institution:
"KEMRI-Wellcome Trust Programme, Centre for Geographic Medicine Resarch-Coast, Nairobi, Kenya", "London School of Hygiene & Tropical Medicine, London, UK"
Department:
Health Policy Unit
Role:
Author
More by this author
Institution:
"KEMRI-Wellcome Trust Programme, Centre for Geographic Medicine Resarch-Coast, Nairobi, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Clinical Vaccinology and Tropical Medicine,Centre for (CCVTM)
Role:
Author
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Funding agency for:
English, M
Grant:
076827
More from this funder
Funding agency for:
Snow, R
Grant:
079080
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
6
Issue:
1
Article number:
e1000015
Publication date:
2009-01-06
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Language:
English
Keywords:
UUID:
uuid:ceea4678-4b4e-4c32-a782-41173e1d3953
Local pid:
ora:2723
Deposit date:
2009-03-24

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