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Capecitabine: Have we got the dose right?

Abstract:

In the past 5-10 years there has been a growing trend for substituting conventional 5-fluorouracil with the oral prodrug of 5-fluorouracil, capecitabine, in chemotherapy regimens. This regimen change is based on evidence of the efficacy equivalence of these two drugs and the lack of an increase in overall toxic effects when capecitabine is used. Many investigators in different parts of the world have determined their own starting dose for capecitabine, usually based on their experience of tox...

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Publisher copy:
10.1038/ncponc1240

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Journal:
Nature Clinical Practice Oncology More from this journal
Volume:
6
Issue:
1
Pages:
17-24
Publication date:
2009-01-01
DOI:
EISSN:
1743-4262
ISSN:
1743-4254
Language:
English
Pubs id:
pubs:178739
UUID:
uuid:cec8aa87-0d96-4d5f-a296-2a058a8ed20f
Local pid:
pubs:178739
Source identifiers:
178739
Deposit date:
2012-12-19

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