Journal article icon

Journal article

Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR trial.

Abstract:

PURPOSE: Laboratory and case-control studies suggest a pivotal role for the cyclooxygenase-2 (COX-2) pathway in colorectal carcinogenesis. The purpose of this study was to test whether the COX-2 inhibitor rofecoxib could reduce recurrence and improve survival when administered in the adjuvant setting of colorectal cancer (CRC). PATIENTS AND METHODS: Patients who had undergone potentially curative surgery and completion of adjuvant therapy for stage II and III CRC were randomly assigned to re...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1200/jco.2010.29.6244

Authors


Midgley, RS More by this author
McConkey, CC More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Expand authors...
Journal:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Volume:
28
Issue:
30
Pages:
4575-4580
Publication date:
2010-10-05
DOI:
EISSN:
1527-7755
ISSN:
0732-183X
URN:
uuid:cec2e818-1f01-4cba-8915-e1b2610dfb2f
Source identifiers:
257431
Local pid:
pubs:257431

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP