Journal article icon

Journal article

Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease.

Abstract:

BACKGROUND: Alternative gene transcript splicing permits a single gene to produce multiple proteins with varied functions. Bioinformatic investigations have identified numerous splice variants, but whether these transcripts are translated to functional proteins and the physiological significance of these alternative proteins are largely unknown. Through direct identification of splice variants associated with disease states, we can begin to address these questions and to elucidate their roles...

Expand abstract

Actions


Access Document


Publisher copy:
10.1186/gb-2007-8-3-r32

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Genome biology More from this journal
Volume:
8
Issue:
3
Pages:
R32
Publication date:
2007-01-01
DOI:
EISSN:
1465-6914
ISSN:
1465-6906
Language:
English
Keywords:
Pubs id:
pubs:461741
UUID:
uuid:cebdccfd-40ba-4f8f-8471-310c657a292d
Local pid:
pubs:461741
Source identifiers:
461741
Deposit date:
2014-06-02

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP