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Characterization of polymyositis infiltrates using monoclonal antibodies to human leucocyte antigens.

Abstract:

Frozen serial sections of muscle from 15 patients with polymyositis and three normal controls were studied by indirect immunofluorescence with a panel of mouse monoclonal antibodies to various human leucocyte components. The results showed good correlation with conventional histology. In addition, large numbers of T lymphocytes were identified in those cases with a marked inflammatory infiltrate. Many of the T cells probably bear HLA-DR antigen as the anti-HLA-DR antibody stained as many cell...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Clinical and experimental immunology
Volume:
45
Issue:
2
Pages:
290-298
Publication date:
1981-08-01
EISSN:
1365-2249
ISSN:
0009-9104
Source identifiers:
35563
Language:
English
Keywords:
Pubs id:
pubs:35563
UUID:
uuid:ceba9b18-3609-451e-a294-16b24bad1c80
Local pid:
pubs:35563
Deposit date:
2012-12-20

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