Journal article
Group II metabotropic glutamate receptors mediate presynaptic inhibition of excitatory transmission in pyramidal neurons of the human cerebral cortex
- Abstract:
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Group II metabotropic glutamate receptor (mGluR) ligands are potential novel drugs for neurological and psychiatric disorders, but little is known about the effects of these compounds at synapses of the human cerebral cortex. Investigating the effects of neuropsychiatric drugs in human brain tissue with preserved synaptic circuits might accelerate the development of more potent and selective pharmacological treatments. We have studied the effects of group II mGluR activation on excitatory syn...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 3.6MB)
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- Publisher copy:
- 10.3389/fncel.2018.00508
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Authors
Funding
National Institute for Health Research
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Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Cellular Neuroscience Journal website
- Volume:
- 12
- Article number:
- 508
- Publication date:
- 2019-01-08
- Acceptance date:
- 2018-12-07
- DOI:
- ISSN:
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1662-5102
- Source identifiers:
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952075
Item Description
- Pubs id:
-
pubs:952075
- UUID:
-
uuid:ceb8a8cc-312b-402c-84ea-2e9c1ca4f9ae
- Local pid:
- pubs:952075
- Deposit date:
- 2018-12-19
Terms of use
- Copyright holder:
- Bocchio, et al
- Copyright date:
- 2019
- Notes:
- © 2019 Bocchio, Lukacs, Stacey, Plaha, Apostolopoulos, Livermore, Sen, Ansorge, Gillies, Somogyi and Capogna. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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