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Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins.

Abstract:

Post-translational modification (PTM) of proteins plays an important part in mediating protein interactions and/or the recruitment of specific protein targets. PTM can be mediated by the addition of functional groups (for example, acetylation or phosphorylation), peptides (for example, ubiquitylation or sumoylation), or nucleotides (for example, poly(ADP-ribosyl)ation). Poly(ADP-ribosyl)ation often involves the addition of long chains of ADP-ribose units, linked by glycosidic ribose-ribose bo...

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Publisher copy:
10.1038/nature06420

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Matsusaka, T More by this author
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Journal:
Nature
Volume:
451
Issue:
7174
Pages:
81-85
Publication date:
2008-01-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:ceb7749f-d078-468c-9b34-e2ef00cc18fb
Source identifiers:
376190
Local pid:
pubs:376190

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