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"Site-selected" transposon mutagenesis of Drosophila.

Abstract:

Despite the wide range of techniques that can be brought to bear on the study of basic processes in Drosophila, there are still deficiencies in our armory. One of these is an ability to select mutants in cases where the gene is known and has been cloned, but where we are ignorant of the associated phenotype. We describe here a solution to this problem as applied to a model system, the singed (sn) locus. Our method is a combination of classical genetics and molecular biology: sib selection plu...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.87.5.1686

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
87
Issue:
5
Pages:
1686-1690
Publication date:
1990-03-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:ce94ecf8-accb-4929-b803-565a03606970
Source identifiers:
315592
Local pid:
pubs:315592

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