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Journal article

Atherosclerosis regression.

Abstract:

Atherosclerosis follows the deposition, retention, and oxidative modification of lipoproteins, especially low-density lipoprotein (LDL) in the walls of large arteries. Uptake of oxidized LDL results in the formation of macrophage foam cells. Proliferation of vascular smooth muscle cells and secretion of extracellular matrix contribute "fibrous" components of the plaque, whereas ongoing accumulation of lipid and inflammatory cell debris forms the necrotic lipid core of the mature atherosclerot...

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Publisher copy:
10.1007/s11936-008-0020-2

Authors


Lindsay, AC More by this author
Kylintireas, I More by this author
Choudhury, RP More by this author
Journal:
Current treatment options in cardiovascular medicine
Volume:
10
Issue:
3
Pages:
187-194
Publication date:
2008-06-05
DOI:
EISSN:
1534-3189
ISSN:
1092-8464
URN:
uuid:ce7be4d4-617f-41ce-88db-07f51d8a39b9
Source identifiers:
151935
Local pid:
pubs:151935
Language:
English

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