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The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like Loci.

Abstract:

The innate and adaptive immune systems of vertebrates possess complementary, but intertwined functions within immune responses. Receptors of the mammalian innate immune system play an essential role in the detection of infected or transformed cells and are vital for the initiation and regulation of a full adaptive immune response. The genes for several of these receptors are clustered within the leukocyte receptor complex (LRC). The purpose of this study was to carry out a detailed analysis o...

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Authors


Coggill, P More by this author
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Journal:
PLoS genetics
Volume:
2
Issue:
5
Publication date:
2006-05-05
DOI:
EISSN:
1553-7404
URN:
uuid:ce6e96d2-dcb6-41d6-9f38-ab5329ebefb7
Source identifiers:
95157
Local pid:
pubs:95157
Language:
English

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