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The role of the small GTPase, arf-3, in seam cell development and secretion in C. elegans

Abstract:

The Caenorhabditis elegans seam cell lineage provides a useful model to study stem cell biology and the regulation of cellular division and differentiation. Seam cells are a population of stem-like cells that run along the length of the worm which divide both symmetrically, to expand the pool of progenitor cells, and asymmetrically to generate various differentiated cells including hypodermal and neuronal cells.

The seam cells also have a secretory function; giving rise to the c...

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Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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