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Plasmodium falciparum malaria in children aged 0-2 years: the role of foetal haemoglobin and maternal antibodies to two asexual malaria vaccine candidates (MSP3 and GLURP)

Abstract:

BACKGROUND: Children below six months are reported to be less susceptible to clinical malaria. Maternally derived antibodies and foetal haemoglobin are important putative protective factors. We examined antibodies to Plasmodium falciparum merozoite surface protein 3 (MSP3) and glutamate-rich protein (GLURP), in children in their first two years of life in Burkina Faso and their risk of malaria. METHODS: A cohort of 140 infants aged between four and six weeks was recruited in a stable transmis...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pone.0107965

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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS ONE Journal website
Volume:
9
Issue:
9
Pages:
e107965
Publication date:
2014-09-19
Acceptance date:
2014-08-07
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Source identifiers:
485464
Language:
English
UUID:
uuid:ce66eeba-ba2a-41a8-91ac-da196a606d22
Local pid:
pubs:485464
Deposit date:
2014-10-02

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