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Journal article

mTORC inhibitors as broad-spectrum therapeutics for age-related diseases

Abstract:

Chronological age represents the greatest risk factor for many life-threatening diseases, including neurodegeneration, cancer, and cardiovascular disease; ageing also increases susceptibility to infectious disease. Current efforts to tackle individual diseases may have little impact on the overall healthspan of older individuals, who would still be vulnerable to other age-related pathologies. However, recent progress in ageing research has highlighted the accumulation of senescent cells with ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3390/ijms19082325

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Oxford college:
Oriel College
Role:
Author
ORCID:
0000-0002-5306-285X
Publisher:
MDPI Publisher's website
Journal:
International Journal of Molecular Sciences Journal website
Volume:
19
Issue:
8
Article number:
2325
Publication date:
2018-08-08
Acceptance date:
2018-07-30
DOI:
ISSN:
1422-0067
Pmid:
30096787
Source identifiers:
909237
Language:
English
Keywords:
Pubs id:
pubs:909237
UUID:
uuid:ce5b8da7-39ff-472d-9a9f-559fe78fc26f
Local pid:
pubs:909237
Deposit date:
2019-01-07

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