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Journal article

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.

Abstract:

The inflammatory bowel diseases (IBDs), Crohn's disease (CD) and ulcerative colitis, are chronic inflammatory disorders of the digestive tract. The pathogenesis of IBD is complicated, and it is widely accepted that immunologic, environmental and genetic components contribute to its etiology. To identify genetic susceptibility factors in CD, we performed a genome-wide association study in Japanese patients and controls using nearly 80,000 gene-based single nucleotide polymorphism (SNP) markers...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddi379

Authors


Yamazaki, K More by this author
McGovern, D More by this author
Ragoussis, J More by this author
Paolucci, M More by this author
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Journal:
Human molecular genetics
Volume:
14
Issue:
22
Pages:
3499-3506
Publication date:
2005-11-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:ce51c969-e109-43b0-8551-6366645eb444
Source identifiers:
71814
Local pid:
pubs:71814

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