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Journal article

RNA enzymes as tools for gene ablation.

Abstract:

Ribozymes have the potential to ablate the expression of any gene in a sequence-specific manner and, therefore, may be useful as therapeutic molecules or as tools for the analysis of gene function. Although a number of reports have described ribozymes that are effective in inhibiting gene expression, few studies have attempted, systematically, to analyze the features of ribozymes that affect their potency within cells. Experimental observations suggest that emerging rules governing ribozyme p...

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Journal:
Current opinion in biotechnology More from this journal
Volume:
6
Issue:
1
Pages:
44-49
Publication date:
1995-02-01
DOI:
EISSN:
1879-0429
ISSN:
0958-1669
Language:
English
Keywords:
Pubs id:
pubs:21086
UUID:
uuid:ce50d52a-e0b0-4796-9cb0-0dc71a2716e8
Local pid:
pubs:21086
Source identifiers:
21086
Deposit date:
2012-12-19

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