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Journal article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Abstract:

Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation of disability. Epidemiological studies have shown that genetic factors are primarily responsible for the substantially increased frequency of the disease seen in the relatives of affected individuals, and systematic attempts to identify linkage in multiple...

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Publication status:
Published

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Publisher copy:
10.1038/nature10251

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Journal:
Nature
Volume:
476
Issue:
7359
Pages:
214-219
Publication date:
2011-08-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Source identifiers:
179391

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