Antilymphocytic antibodies and marrow transplantation. VII. Two of nine monoclonal anti-Thy-1 antibodies used for pretreatment of donor marrow suppressed graft-versus-host reactions without added complement.

Thierfelder, S; Cobbold, S; Kummer, U; Waldmann, H; Schuh, R

Abstract:

Eleven monoclonal antibodies of rat or mouse origin against the mouse pan T antigen Thy-1 were compared for their ability to reduce mortality from graft-versus-host disease (GVHD) when incubated with donor marrow. Spleen and bone marrow cells were transferred to F1 hybrids or to fully allogeneic (H-2 I-A incompatible) mice. Particular attention was paid to whether complement (rabbit) enhanced the anti-GVHD effect of the antibodies in homozygous histoincompatible chimeras: without complement, ...

Expand abstract

Publication status:

Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Thierfelder, S., Cobbold, S., Kummer, U., Waldmann, H., & Schuh, R. (1985). Antilymphocytic antibodies and marrow transplantation. VII. Two of nine monoclonal anti-Thy-1 antibodies used for pretreatment of donor marrow suppressed graft-versus-host reactions without added complement. Experimental Hematology, 13(9), 948–955.

MLA Style

Thierfelder, S., et al. “Antilymphocytic Antibodies and Marrow Transplantation. VII. Two of Nine Monoclonal Anti-Thy-1 Antibodies Used for Pretreatment of Donor Marrow Suppressed Graft-versus-Host Reactions without Added Complement.” Experimental Hematology, vol. 13, no. 9, 1985, pp. 948–55.

Chicago Style

Thierfelder, S, S Cobbold, U Kummer, H Waldmann, and R Schuh. 1985. “Antilymphocytic Antibodies and Marrow Transplantation. VII. Two of Nine Monoclonal Anti-Thy-1 Antibodies Used for Pretreatment of Donor Marrow Suppressed Graft-versus-Host Reactions without Added Complement.” Experimental Hematology 13 (9): 948–55.
Tweet
Print