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Journal article

Haplotype mapping of the bronchiolitis susceptibility locus near IL8.

Abstract:

Susceptibility to viral bronchiolitis, the commonest cause of infant admissions to hospital in the industrialised world, is associated with polymorphism at the IL8 locus. Here we map the genomic boundaries of the disease association by case-control analysis and TDT in 580 affected UK infants. Markers for association mapping were chosen after determining patterns of linkage disequilibrium across the surrounding region of chromosome 4q, a 550-kb segment containing nine genes, extending from AFP...

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Publication status:
Published

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Publisher copy:
10.1007/s00439-003-1038-x

Authors


Rowlands, K More by this author
Lockhart, E More by this author
Sharland, M More by this author
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Journal:
Human genetics
Volume:
114
Issue:
3
Pages:
272-279
Publication date:
2004-02-05
DOI:
EISSN:
1432-1203
ISSN:
0340-6717
URN:
uuid:ce09ba81-9752-48a5-895b-c12715474114
Source identifiers:
32536
Local pid:
pubs:32536

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