Journal article icon

Journal article

Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits.

Abstract:

A clone was isolated from a cDNA library from early embryos of Xenopus laevis that codes for a highly charged protein containing 339 amino acids. Two putative nuclear localization signals could be identified in its sequence, but no other known motifs or domains. Closely related ORFs are present in the genomes of man, C. elegans, yeast and Arabidopsis. A fusion protein with GFP expressed in HeLa cells or Xenopus oocytes was found to be localized in the nucleolus and coiled (Cajal) bodies. More...

Expand abstract

Actions


Access Document


Publisher copy:
10.1515/bc.2001.199

Authors


Bogengruber, E More by this author
Hallegger, M More by this author
Doppler, E More by this author
Lepperdinger, G More by this author
Expand authors...
Journal:
Biological chemistry
Volume:
382
Issue:
12
Pages:
1637-1647
Publication date:
2001-12-05
DOI:
EISSN:
1437-4315
ISSN:
1431-6730
URN:
uuid:ce038684-41cc-4bf6-8b38-f6f53cbfde93
Source identifiers:
334663
Local pid:
pubs:334663

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP