Menopausal hormone therapy and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition.

Journal article

Menopausal hormone therapy (HT) may influence colorectal cancer risk. A total of 136,275 postmenopausal women from the European Prospective Investigation into Cancer and Nutrition were followed for an average of 9 years, during which time 1,186 colorectal cancers were diagnosed. Hazard ratios (HR) and 95% confidence intervals (CI) were estimated using Cox proportional hazards models stratified by center and age, and adjusted for body mass index, smoking, diabetes, physical activity and alcoho...

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Authors: Tsilidis, K; Allen, N; Key, T; Sanjoaquin, M; Bakken, K

• Publication status: Published
• Journal: International journal of cancer. Journal international du cancer
• Volume: 128
• Issue: 8
• Pages: 1881-1889
• Publication date: 2011-04-01
• DOI: 10.1002/ijc.25504
• EISSN: 1097-0215
• ISSN: 0020-7136
• Language: English
• Keywords: Cohort Studies; European Continental Ancestry Group; Questionnaires; Nutritional Sciences; Prospective Studies; Hormone Replacement Therapy; Postmenopause; Female; Middle Aged; Risk Factors; Humans; Proportional Hazards Models; Colorectal Neoplasms; Prognosis